Caffeine+Diphenhydramine+Paracetamol+Phenylephrine is used in the treatment of common cold symptoms with fever.

This is a combination of four medicines: Caffeine, Diphenhydramine, Paracetamol, and Phenylephrine which relieve cold symptoms. Diphenhydramine is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that are responsible for pain and fever. Caffeine increases the effectiveness of paracetamol and makes you more alert. Phenylephrine is a decongestant which narrows the small blood vessels providing temporary relief from congestion or stuffiness in the nose.

Nausea, Vomiting, Stomach pain / epigastric pain, Insomnia (difficulty in sleeping), Restlessness, Allergic reaction, Sleepiness, Dizziness, Coordination impaired, Thickened respiratory tract secretions, Headache