Glibenclamide+Metformin+Pioglitazone is used in the treatment of type 2 diabetes.

This is a combination of three antidiabetic medicines: Glibenclamide, metformin and pioglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glibenclamide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which decreases the production and absorption of sugar in your body and allows better use of existing insulin. Pioglitazone is a thiazolidinedione which works by increasing the body's sensitivity to insulin.

Hypoglycemia (low blood sugar level), Altered taste, Nausea, Diarrhoea, Stomach pain, Headache, Edema, Weight gain, Anemia, Bone fracture, Blurred vision, Upper respiratory tract infection