Isosorbide Dinitrate+Hydralazine is used in the treatment of heart failure.

This is a combination of two medicines: Isosorbide dinitrate and hydralazine. Isosorbide dinitrate is a nitrate which relaxes the blood vessels and decreases the oxygen demand of the heart. Hydralazine is a potassium channel opener which acts as an antioxidant and lessens tolerance to isosorbide dinitrate, thereby preserving its capacity to relax blood vessels. Together, they improve symptoms of heart failure.

Nausea, Vomiting, Diarrhoea, Loss of appetite, Headache, Flushing of face, Dizziness, Increased heart rate, Orthostatic hypotension (sudden lowering of blood pressure on standing), Chest pain, Drug-induced lupus syndrome, Palpitations, Decreased blood pressure, Swelling of hands, Swelling of feet