Doxepin is used in the treatment of depression and insomnia.
It is used in patients intolerant of or unresponsive to alternative treatment options for depression.

Doxepin increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

Sleepiness, Blurred vision, Increased heart rate, Weight gain, Dryness in mouth, Orthostatic hypotension (sudden lowering of blood pressure on standing), Constipation, Difficulty in urination

• The main dose should be taken at night as this drug may produce drowsiness or sleepiness.
• It can take 4 to 6 weeks for Doxepin to start working.
• You should continue the treatment for at least 6 months after you feel better to stop depression from coming back.
• If your doctor asks you to stop Doxepin, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly.
• Avoid driving or operating machinery as it may decrease alertness.
• Avoid consuming alcohol when taking the Doxepin, as it may cause excessive drowsiness and calmness.
• The addiction/dependence potential of Doxepin is very less.
• It may be extremely dangerous in overdose.

Ques. Q. Is Doxepin a tricyclic antidepressant, SSRI/ MAO inhibitor?
Doxepin is a tricyclic antidepressant. It is not a SSRI (selective serotonin reuptake inhibitor) or a MAOi (monoamine oxidase inhibitor)

Ques. Q. Is Doxepin a habit-forming/addictive or narcotic drug?
No. Doxepin is not a habit-forming/addictive or narcotic drug. It might however cause certain withdrawal effects when the treatment is stopped abruptly. Hence, it is advisable to consult your doctor before stopping the treatment

Ques. Q. Is Doxepin a sedative or sleeping pill?
No. Doxepin is not a sedative or sleeping pill. However it might cause sleepiness as a side-effect

Ques. Q. Is Doxepin safe?
Yes. Doxepin is relatively safe if used as recommended. In case of any side-effects, consult your doctor

Ques. Q. Can I take doxepin with hydroxyzine, Ambien, Zoloft, Percocet, Wellbutrin, NyQuil, Atarax, Lunesta, and Prozac?
Doxepin should not be taken with Zoloft (sertraline), Prozac (Fluoxetine), Wellbutrin (bupropion), Lunesta (eszopiclone), NyQuil (cold and flu medication), Percocet (oxycodone, acetaminophen), Prozac (fluoxetine), Atarax (hydroxyzine) and Ambien (zolpidem)

Ques. Q. Does Doxepin cause weight gain, sleepiness or hair loss?
Doxepin may cause weight gain, sleepiness or hair loss. If you experience any such symptoms, please consult your doctor

Ques. Q. Does Doxepin help with pain or anxiety?
Doxepin may be effective in the treatment of chronic neuropathic pain and anxiety.