Hydroxyurea is used in the treatment of sickle cell anemia.
How Hydroxyurea worksHydroxycarbamide causes inhibition of DNA synthesis during the S-phase of cell division by acting as a ribonucleotide reductase inhibitor resulting to cell death. It is S-phase specific.
Common side effects of HydroxyureaMegaloblastic anemia, Decreased white blood cell count (neutrophils), Oligospermia (low sperm count), Azoospermia (absence of sperms)
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